View full article | Melatonin and the Gut Significant quantities of melatonin are produced in the human digestive tract. Melatonin has multiple effects on digestion and is important in maintaining normal digestive function. It may have clinical use in treating a range of gastrointestinal disorders, including gastroesophageal reflux disease, gastric ulceration, pancreatitis, liver fibrosis, irritable bowel syndrome, and ulcerative colitis. Clinicians are encouraged to consider […]